Biopharmaceutical Grade TPE Tubing

AdvantaFlex addresses the need for a flexible, translucent, sterilizable, moldable, heat sealable, and weldable biopharmaceutical tubing for fluid processing. AdvantaFlex TPE tubing maintains its physical properties following sterilization processes, resists kinking, remains translucent for visible product flow, and does not become gummy.

welded AdvantaFlex tubing AdvantaFlex heat seal

KEY FEATURES

  • Sterile weldable and heat sealable
  • Available as leak-proof molded connections and tubing
  • Made from FDA-approved ingredients
  • Animal Derived Ingredient FreeCertified free of silicone oils and animal-derived ingredients
  • Sterilizable by autoclave or gamma radiation
  • Available with validated sterility assurance of 10-6 via gamma irradiation per ISO 11137 method VDmax 25
  • Meets various ISO and USP standards, including Class VI
  • Meets European Pharmacopoeia 3.2.2.1 standards
  • REACH, RoHS and California Proposition 65 compliant
  • Excellent low absorption and adsorption characteristics as compared to silicone
  • Low permeability as compared to silicone
  • Smooth interior for excellent flow and performance
  • Translucent for fluid flow visibility
  • Excellent tubing component for Single-Use systems
  • Sizes from 1/8" (.125) through 1" (1.000) I.D.
  • Custom lengths, sizes, and packaging available
  • Supplied double bagged
  • Sealed in polybags at manufacture for cleanliness
  • Documented quality control; lot traceable with identification on polybags
  • Single resin validation — no need to graft to other tubing materials like silicone for media filling and sampling applications that involve peristaltic pumps; helps eliminate operator errors
  • "Extractables" test portfolio available
  • AdvantaFlex has a Master File with the U.S. Food and Drug Administration (#28810)
  • Complete validation package available upon request

There is a Better Alternative
Discover how much better the right tubing — AdvantaFlex — will work in 
your pharmaceutical, biotech, medical, or other critical processing application.

AdvantaFlex Weld Strength

Weld Test Video

APPLICATIONS

  • AdvantaFlex with bagsSterile filling
  • Vaccine production
  • Pharmaceutical sampling and delivery systems
  • Single-use systems
  • Bioreactor processes
  • Cell media, harvesting, and fermentation
  • Pharmaceutical production and processing
  • High purity water transfer
  • Filtration

Because of its ability to be sealed and welded, AdvantaFlex is ideal for filling and sampling applications.

SPECIFICATIONS

ADVANTAFLEX® - BIOPHARMACEUTICAL GRADE TPE

AdvantaFlex Biopharmaceutical TPE tubing
Part
Number		 I.D. Wall
(reference)		 O.D. Working Pressure
at 70°F (21.1°C)		 Standard Lengths
Coiled		 Standard Lengths
on Spools
  (in.) (mm.) (in.) (mm.) (in.) (mm.) PSI Bar (ft.) (ft.)
APAF-BP-0125-0250 .125 3.18 .062 1.57 .250 6.35 30 2.1 50, 100 500
APAF-BP-0188-0313 .188 4.76 .062 1.57 .313 7.94 23 1.6 50, 100 -
APAF-BP-0188-0375 .188 4.76 .094 2.38 .375 9.52 32 2.2 50, 100 -
APAF-BP-0250-0375 .250 6.35 .063 1.59 .375 9.52 20 1.4 50, 100 -
APAF-BP-0250-0438 .250 6.35 .094 2.38 .438 11.11 23 1.6 50, 100 300
APAF-BP-0250-0500 .250 6.35 .125 3.18 .500 12.70 30 2.1 50 -
APAF-BP-0313-0438 .313 7.94 .062 1.57 .438 11.11 21 1.4 50, 100 300
APAF-BP-0313-0500 .313 7.94 .094 2.38 .500 12.70 24 1.6 50 -
APAF-BP-0375-0500 .375 9.52 .062 1.57 .500 12.70 18 1.3 100 -
APAF-BP-0375-0563 .375 9.52 .094 2.39 .563 14.30 23 1.6 50 -
APAF-BP-0375-0625 .375 9.52 .125 3.18 .625 15.88 24 1.6 50, 100 150
APAF-BP-0500-0750 .500 12.70 .125 3.18 .750 19.09 22 1.5 50, 100 100
APAF-BP-0625-0875 .625 15.88 .125 3.18 .875 22.23 18 1.3 50 -
APAF-BP-0750-1000 .750 19.05 .125 3.18 1.000 25.40 17 1.2 50, 100 75
APAF-BP-0750-1125 .750 19.05 .188 4.76 1.125 28.58 18 1.3 100 -
APAF-BP-1000-1375 1.000 25.40 .188 4.76 1.375 34.93 18 1.3 25 -

Sold by standard lengths only. Add length suffix code to product number when ordering—see the Coil Length Legend at right for length suffix codes. Example: a 50 foot coil of .125 inch I.D. x .250 inch O.D. tubing is product number APAF-BP-0125-0250L. Add length and "S" to denote "spool" for products with lengths available on spools. Example: a 500 foot spool of .125 inch I.D. x .250 inch O.D. tubing is product number APAF-BP-0125-0250-500S. Working pressures are calculated from burst testing using a 3:1 safety factor. Coils and spools are supplied double bagged in heat-sealed polybags and bulk packed. Contact your AdvantaPure Sales Representative for other packaging options.

The data listed throughout this web site is meant only as a guide to aid in design, and is believed to be reliable; however, nothing stated shall constitute a guarantee or warranty for any application. Product field-testing should be performed to find the actual values for a specific application.

Coil Length Legend

P = 25 feet
L = 50 feet
K = 100 feet

PDF Download a printable version of the AdvantaFlex Datasheet.